Novel Mid-IR ultrafast fibre lasers for molecular vibrational sensing technologies
Speaker: Maria Chernysheva, Aston University
Title: Novel Mid-IR ultrafast fibre lasers for molecular vibrational sensing technologies
Abstract: Mid-infrared vibrational absorption bands are characteristic signatures of all bio-molecules, associated with chemical bonds in a tissue sample. Therefore, vibration spectroscopy is a promising technology for non-invasive assessment of the structure and biochemical content of tissues. Historically, all fibre lasers relied on silica glass fibres, non-transparent beyond 2.5μm; that did not allow extensive application of fibre based laser systems for mid-infrared spectroscopy of water-based proteins. In my talk I will discuss novel glass matrixes and designs of optical fibres and unique materials essential for the development of femtosecond fibre lasers and super continuum sources reaching the mid-infrared range. I will talk about the potential of the development of a mid-infrared vibrational spectroscopy methodology to detect small spectral changes between healthy and diseased cells or tissues, particularly for early cancer diagnostics.